Remodeling in Aortic Stenosis With Reduced and Preserved Ejection Fraction: Insight on Motion Abnormality Via 3D+Time Personalized LV Modeling in Cardiac MRI

• Main Authors: Chuah, Shoon Hui, Tan, Li Kuo, Sari, Nor Ashikin Md, Chan, Bee Ting, Hasikin, Khairunnisa, Lim, Einly, Ung, Ngie Min, Aziz, Yang Faridah Abdul, Jayabalan, Jeyaraaj, Liew, Yih Miin
• Format: Article
• Published: Wiley 2024
• Subjects: R Medicine (General)
• Online Access: http://eprints.um.edu.my/46034/; https://doi.org/10.1002/jmri.28915
• Institution: Universiti Malaya

Background: Increased afterload in aortic stenosis (AS) induces left ventricle (LV) remodeling to preserve a normal ejection fraction. This compensatory response can become maladaptive and manifest with motion abnormality. It is a clinical challenge to identify contractile and relaxation dysfunction...