Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton

Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton

Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5),...

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Main Authors: Primus, Phoebe Sussana, Wu, Carol Hsin-Yi, Kao, Chai-Lin, Choo, Yeun-Mun
Format: Article
Published: Taylor & Francis 2024
Subjects:
QD Chemistry
Online Access:http://eprints.um.edu.my/46089/
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Institution: Universiti Malaya
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spelling my.um.eprints.460892024-08-13T06:53:33Z http://eprints.um.edu.my/46089/ Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton Primus, Phoebe Sussana Wu, Carol Hsin-Yi Kao, Chai-Lin Choo, Yeun-Mun QD Chemistry Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay. Taylor & Francis 2024-04 Article PeerReviewed Primus, Phoebe Sussana and Wu, Carol Hsin-Yi and Kao, Chai-Lin and Choo, Yeun-Mun (2024) Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton. Natural Product Research, 38 (8). pp. 1406-1413. ISSN 1478-6419, DOI https://doi.org/10.1080/14786419.2022.2147932 <https://doi.org/10.1080/14786419.2022.2147932>. 10.1080/14786419.2022.2147932
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic QD Chemistry
spellingShingle QD Chemistry
Primus, Phoebe Sussana
Wu, Carol Hsin-Yi
Kao, Chai-Lin
Choo, Yeun-Mun
Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
description Two new bisanthraquinones, glabraquinone A and B (1-2) were isolated from the root of Prismatomeris glabra (Korth.) Valeton. In addition to the new glabraquinones, six known anthraquinones, that is, 1-hydroxy-2-methoxy-6-methylanthraquinone (3), 1,2-dimethoxy-7-methylanthraquinone (4), lucidin (5), nordamnacanthal (6), damnacanthal (7) and 2-carboxaldehyde-3-hydroxyanthraquinone (8)) and an aromatic compound, that is, catechol diethyl ether (9) were isolated and characterized in this study. Compounds 1, 4 and 9 showed mild activity, reducing N2A cell viability to 77%, 82% and 77%, respectively, in anti-neuroblastoma assay.
format Article
author Primus, Phoebe Sussana
Wu, Carol Hsin-Yi
Kao, Chai-Lin
Choo, Yeun-Mun
author_facet Primus, Phoebe Sussana
Wu, Carol Hsin-Yi
Kao, Chai-Lin
Choo, Yeun-Mun
author_sort Primus, Phoebe Sussana
title Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
title_short Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
title_full Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
title_fullStr Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
title_full_unstemmed Glabraquinone A and B, new bisanthraquinones from Prismatomeris glabra (Korth.) Valeton
title_sort glabraquinone a and b, new bisanthraquinones from prismatomeris glabra (korth.) valeton
publisher Taylor & Francis
publishDate 2024
url http://eprints.um.edu.my/46089/
_version_ 1809136926181031936

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