Peripheral PDLIM5 expression in bipolar disorder and the effect of olanzapine administration

• Main Authors: Zain, M.A., Jahan, S.N., Reynolds, G.P., Zainal, N.Z., Kanagasundram, S., Mohamed, Z.
• Format: Article
• Language: English
• Published: 2012
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/5033/1/Peripheral_PDLIM5_expression_in_bipolar_disorder_and_the_effect_of_olanzapine_administration.pdf; http://eprints.um.edu.my/5033/
• Institution: Universiti Malaya

Background: One of the genes suggested to play an important role in the pathophysiology of bipolar disorder (BPD) is PDLIM5, which encodes LIM domain protein. Our main objective was to examine the effect of olanzapine treatment on PDLIM5 mRNA expression in the peripheral blood leukocytes of BPD pati...