Docking of noncompetitive inhibitors into dengue virus type 2 protease: understanding the interactions with allosteric binding sites

A group of flavanones and their chalcones, isolated from Boesenbergia rotunda L., were previously reported to show varying degrees of noncompetitive inhibitory activities toward Dengue virus type 2 (Den2) protease. Results obtained from automated docking studies are in agreement with experimental da...

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Bibliographic Details
Main Authors: Othman, R., Kiat, T.S., Khalid, N., Yusof, R., Newhouse, E.I., Newhouse, J.S., Alam, M., Rahman, N.A.
Format: Article
Published: 2008
Subjects:
Online Access:http://eprints.um.edu.my/5928/
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Institution: Universiti Malaya