The use of the amplification refractory mutation system (arms) in the detection of rare beta-thalassemia mutations in the Malays and Chinese in Malaysia

• Main Authors: Chan, Yoke Fun, Tan, Kim Lim, Wong, Yean Ching, Wee, Yong Chui, Yap, Sook Fan, Tan, Mary Anne Jin Ai
• Format: Article
• Language: English
• Published: SEAMEO Regional Tropical Medicine and Public Health Network 2001
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/7342/1/The_use_of_the_amplification_refractory_mutation_system_%28arms%29_in_the_detection_of_rare_beta-thalassemia_mutations_in_the_Malays_and_Chinese_in_Malaysia.pdf; http://eprints.um.edu.my/7342/; https://www.tm.mahidol.ac.th/seameo/2001-32-4/30-872-879.pdf
• Institution: Universiti Malaya

Molecular characterization and prenatal diagnosis for beta-thalassemia can be carried out using the Amplification Refractory Mutation System (ARMS). The ARMS is a rapid and direct molecular technique in which beta-thalassemia mutations are visualized immediately after DNA amplification by gel electr...