The Kinetic Study On The Effects Of Mixed Aqueous-Organic Solvents On The Rate Of O- And N- Cyclisation Of N-(4 '-Nitrophenyl)Phthalamic Acid

• Main Authors: Ariffin, Azhar, Khan, M.N., Ahmad, W.H.W.
• Format: Article
• Published: 2007
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/8049/; http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=11&SID=X15kP6BDACOiH3JKAnO&page=1&doc=1
• Institution: Universiti Malaya

The pseudo-first-order rate constants (k(obs)) for the intramolecular carboxylic group-assisted cleavage of N-(4'-nitrophenyl)phthalamic acid (1) show nonlinear decrease of similar to 17-fold and similar to 117-fold with the increase in the respective contents of CH3CN (10-80% v/v) and 1,4-diox...