Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrus Merr

Bioactivity-guided fractionation of the lipoxygenase and cyclooxygenase inhibiting constituents from Chisocheton polyandrus Merr

Lipoxygenase (LOX)-inhibiting compounds from the leaves of Chisocheton polyandrus Merr. were isolated in this study using a bioactivity-guided fractionation technique. Two dammarane triterpenoids, dammara-20,24-dien-3-one (1) (IC50 = 0.69 +/- 0.07 mu M) and 24-hydroxydammara-20,25-dien-3-one (2) (IC...

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Bibliographic Details
Main Authors: Chan, K.Y., Mohamad, K., Ooi, A.J.A., Imiyabir, Z., Chung, L.Y.
Format: Article
Language:English
Published: 2012
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/8153/1/Chan-2012-Bioactivity-guided_f.pdf
http://eprints.um.edu.my/8153/
http://www.sciencedirect.com/science/article/pii/S0367326X12001256
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Institution: Universiti Malaya
Language: English

Internet

http://eprints.um.edu.my/8153/1/Chan-2012-Bioactivity-guided_f.pdf
http://eprints.um.edu.my/8153/
http://www.sciencedirect.com/science/article/pii/S0367326X12001256

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