Identification and characterisation of the early differentiating cells in neural differentiation of human embryonic stem cells

• Main Authors: Noisa, P., Ramasamy, T.S., Lamont, F.R., Yu, J.S.L., Sheldon, M.J., Russell, A., Jin, X., Cui, W.
• Format: Article
• Language: English
• Published: Public Library of Science 2012
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/9243/1/Noisa_et_al_2012_Plos_one.pdf; http://eprints.um.edu.my/9243/
• Institution: Universiti Malaya

One of the challenges in studying early differentiation of human embryonic stem cells (hESCs) is being able to discriminate the initial differentiated cells from the original pluripotent stem cells and their committed progenies. It remains unclear how a pluripotent stem cell becomes a lineage-specif...