Low oxygen tension increased fibronectin fragment induced catabolic activities - response prevented with biomechanical signals

• Main Authors: Parker, E., Vessillier, S., Pingguan-Murphy, Belinda, Wan Abas, Wan Abu Bakar, Bader, D.L., Chowdhury, T.T.
• Format: Article
• Language: English
• Published: 2013
• Subjects: T Technology (General); TA Engineering (General). Civil engineering (General)
• Online Access: http://eprints.um.edu.my/9528/1/Low_oxygen_tension_increased_fibronectin_fragment_induced_catabolic_activities_-_response_prevented_with_biomechanical_signals.pdf; http://eprints.um.edu.my/9528/; http://www.ncbi.nlm.nih.gov/pubmed/24286132
• Institution: Universiti Malaya

Introduction: The inherent low oxygen tension in normal cartilage has implications on inflammatory conditions associated with osteoarthritis (OA). Biomechanical signals will additionally contribute to changes in tissue remodelling and influence the inflammatory response. In this study, we investigat...