Molecular signatures of T-cell inhibition in HIV-1 infection

• Main Authors: Larsson, M., Shankar, E.M., Che, K.F., Saeldi, A., Ellegard, R., Barathan, M., Velu, V., Kamarulzaman, A.
• Format: Article
• Language: English
• Published: BioMed Central 2013
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/9592/1/00000544_99598.pdf; http://eprints.um.edu.my/9592/
• Institution: Universiti Malaya

Cellular immune responses play a crucial role in the control of viral replication in HIV-infected individuals. However,the virus succeeds in exploiting the immune system to its advantage and therefore, the host ultimately fails to control the virus leading to development of terminal AIDS. The virus...