Panduratin A, a possible inhibitor in metastasized A549 cells through inhibition of NF-Kappa B Translocation and chemoinvasion

Panduratin A, a possible inhibitor in metastasized A549 cells through inhibition of NF-Kappa B Translocation and chemoinvasion

In the present study, we investigated the effects of panduratin A (PA), isolated from Boesenbergia rotunda, on apoptosis and chemoinvasion in A549 human non-small cell lung cancer cells. Activation of the executioner procaspase-3 by PA was found to be dose-dependent. Caspase-3 activity was significa...

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Bibliographic Details
Main Authors: Cheah, Shiau Chuen, Lai, Siew Li, Lee, Sui Ting, A. Hadi, A. Hamid, Mustafa, Mohd Rais
Format: Article
Language:English
Published: 2013
Subjects:
R Medicine
RM Therapeutics. Pharmacology
Online Access:http://eprints.um.edu.my/9803/1/Panduratin_A_Inhibits_the_Growth_of_A549_Cells_through.pdf
http://eprints.um.edu.my/9803/
http://www.ncbi.nlm.nih.gov/pubmed/23887718
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Institution: Universiti Malaya
Language: English

Internet

http://eprints.um.edu.my/9803/1/Panduratin_A_Inhibits_the_Growth_of_A549_Cells_through.pdf
http://eprints.um.edu.my/9803/
http://www.ncbi.nlm.nih.gov/pubmed/23887718

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