Molecular sequence and structural comparison of BACE1 and BACE2 / Hoda Mirsafian

• Main Author: Mirsafian, Hoda
• Format: Thesis
• Published: 2012
• Subjects: QH301 Biology
• Online Access: http://studentsrepo.um.edu.my/3813/1/1._abstract%2C_content.pdf; http://studentsrepo.um.edu.my/3813/2/2._chap_1_%2D_6.pdf; http://studentsrepo.um.edu.my/3813/3/3._references%2C_appendices.pdf; http://pendeta.um.edu.my/client/default/search/results?qu=Molecular+sequence+and+structural+comparison+of+BACE1+and+BACE2&te=; http://studentsrepo.um.edu.my/3813/
• Institution: Universiti Malaya

Beta-Secretase is a transmembrane aspartic protease that cleaves the amyloid precursor protein (APP) to generate amyloid beta peptide (Aβ) that is believed to be responsible for the Alzheimer’s disease (AD). Beta-Secretaes include BACE1 and BACE2 which are close homologues, sharing 61.5% similarity...