Combination of gravid ovipositing sticky trap and NS1 antigen test: New paradigm for dengue vector surveillance in Selangor Malaysia / Lau Sai Ming
Dengue fever is a serious public health problem in tropical countries and has increased 37 folds in Malaysia compared to decades ago. Selangor, the most developed and populated state in Malaysia has contributed about 50% cases in the country. Vector control has been the hallmark for surveillance...
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| Format: | Thesis |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://studentsrepo.um.edu.my/9189/7/sai_ming.pdf http://studentsrepo.um.edu.my/9189/ |
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| Institution: | Universiti Malaya |
| Summary: | Dengue fever is a serious public health problem in tropical countries and has increased
37 folds in Malaysia compared to decades ago. Selangor, the most developed and
populated state in Malaysia has contributed about 50% cases in the country. Vector
control has been the hallmark for surveillance and control of dengue. However, there is
no correlation between Aedes index and dengue cases. Thus, new proactive paradigms
are necessary for vector surveillance which would help in the prevention of dengue
epidemics in the country. This two-year study was conducted in dengue epidemic urban
area of Selangor; where GOS trap (Gravid Mosquito Ovipositing in Sticky Trap) was
used to capture gravid Aedes mosquitoes. All Aedes mosquitoes were tested with NS1
rapid antigen test kit. All dengue cases from the study site reported to the Ministry of
Health were recorded. Microclimatic data such as rainfall, temperature and humidity were
recorded weekly. Aedes aegypti was the predominant mosquito (95.6%) caught in GOS
traps, 23% (43/187) pools of mosquitoes were positive for virus dengue using the NS1
antigen kit. Confirmed cases were observed with a lag of one week after positive Ae.
aegypti were detected. Aedes aegypti density as analyzed by distributed lag non-linear
models, will increase lag of 2-3 weeks for temperature increase from 28 to 30oC; and lag
of three weeks for increased rainfall. In conclusion, the combined use of GOS trap and
NS1 antigen kit to detect dengue virus in mosquitoes can be used as a new tool for dengue
vector surveillance. It seems to be a proactive method where control action can be
activated when positive mosquitoes are obtained. However, a randomized control trial
needs to be conducted to prove that this paradigm will indeed reduce dengue epidemics. |
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