Comparative study of neem (azadirachta indica), bitter gourd and albendazole (momordica charantia) extract as herbal anthelminti as chemical anthelmintic in controlling gastrointestinal nematodes in goats

• Main Author: Xavier, Priscilla Francis
• Format: Undergraduate Final Project Report
• Published: 2014
• Online Access: http://discol.umk.edu.my/id/eprint/5908/
• Institution: Universiti Malaysia Kelantan

The comparative effects of methanol extracts of Neem (Azadirachta indica), Bitter Gourd (Momordica charantia) and chemical anthelmintic-Albendazole on gastrointestinal nematodes infected goats were evaluated by egg per gram (EPG) count for a period of approximately three weeks. Twelve Kambing Katjang goats naturally infested with gastrointestinal parasite were selected based on EPG count (>300 EPG) and divided into four groups each consisting of three goats. Treatment I was methanol extract of A.indica (0.5 ml/kg body weight), treatment II was methanol extract of M.charantia (1 ml/kg body weight), treatment III was chemical anthelmintic, Albendazole (0.1 ml/kg body weight) and finally treatment IV was control. The treatments were administered on day 0 orally with single dosage and faecal egg count (EPG) was determined on day 4, 8 and 20. Both methanol extract of A.indica and M.charantia showed significant (p<0.01) reduction in controlling gastrointestinal nematodes infected goats compared to control group. A.indica showed gastrointestinal nematodes to be at a safe level (below 300 EPG) in goats on day 20 whereas M.charantia showed efficacy on day 8. Chemical anthelmintic showed no significant (p>0.01) reduction throughout the three weeks. The use of herbal anthelmintics, A.indica and M.charantia significant (p<0.01) anthelmintic activity when compared with control group.