Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia

The experiment involved 4 different racial populations such as Malay (M), Chinese (C), Indian Tamil (I) and confounded population termed as Others (O) from 13 states and 1 federal territory in Malaysia. Methods: A total of 1101 students in Universiti Malaysia Kelantan were surveyed for ABO blood typ...

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Main Authors: Md. Ruhul Amin, Dwi Susanto, Laila Naher
Format: Non-Indexed Article
Published: 2015
Online Access:http://discol.umk.edu.my/id/eprint/8100/
https://www.pmindexing.com/journals/index.php/AJMS/article/view/575
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Institution: Universiti Malaysia Kelantan
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spelling my.umk.eprints.81002022-05-23T10:25:17Z http://discol.umk.edu.my/id/eprint/8100/ Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia Md. Ruhul Amin Dwi Susanto Laila Naher The experiment involved 4 different racial populations such as Malay (M), Chinese (C), Indian Tamil (I) and confounded population termed as Others (O) from 13 states and 1 federal territory in Malaysia. Methods: A total of 1101 students in Universiti Malaysia Kelantan were surveyed for ABO blood type and Rh factor. Results: Phenotypic frequencies were 0.24, 0.27, 0.09 and 0.40 in M; 0.26, 0.21, 0.06 and 0.38 in C; 0.27, 0.31, 0.09 and 0.33 in I and 0.11, 0.29, 0.09 and 0.51 in O for A, B, AB and O blood group, respectively. Rh+ve cases were found to be abundant and distributed as 0.92, 0.94, 0.89 and 0.79 among M, C, I and O race, respectively. Allele frequencies of IA, IB and I were estimated at 0.17, 0.20 and 0.63 in M; 0.19, 0.16 and 0.65 in C; 0.20, 0.23 and 0.57 in O, respectively. Insignificant χ2(0.05, 2 = 5.991) interprets that ABO allele frequencies exist in Hardy-Weinberg equilibrium in all races. However, high magnitude of χ2 in M (5.463) signifies continued admixture in the M genetic population or the population is less stable than C and I. C and I are in more stabilized condition in this regard that might be because of closed breeding within them.Conclusion: Results of this study might be useful to blood transfusion services in Malaysia apart from human population geneticists. 2015 Non-Indexed Article NonPeerReviewed Md. Ruhul Amin and Dwi Susanto and Laila Naher (2015) Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia. Asian Journal of Medical Sciences, 6 (4). pp. 25-29. ISSN 2091-0576 https://www.pmindexing.com/journals/index.php/AJMS/article/view/575
institution Universiti Malaysia Kelantan
building Perpustakaan Universiti Malaysia Kelantan
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Kelantan
content_source UMK Institutional Repository
url_provider http://umkeprints.umk.edu.my/
description The experiment involved 4 different racial populations such as Malay (M), Chinese (C), Indian Tamil (I) and confounded population termed as Others (O) from 13 states and 1 federal territory in Malaysia. Methods: A total of 1101 students in Universiti Malaysia Kelantan were surveyed for ABO blood type and Rh factor. Results: Phenotypic frequencies were 0.24, 0.27, 0.09 and 0.40 in M; 0.26, 0.21, 0.06 and 0.38 in C; 0.27, 0.31, 0.09 and 0.33 in I and 0.11, 0.29, 0.09 and 0.51 in O for A, B, AB and O blood group, respectively. Rh+ve cases were found to be abundant and distributed as 0.92, 0.94, 0.89 and 0.79 among M, C, I and O race, respectively. Allele frequencies of IA, IB and I were estimated at 0.17, 0.20 and 0.63 in M; 0.19, 0.16 and 0.65 in C; 0.20, 0.23 and 0.57 in O, respectively. Insignificant χ2(0.05, 2 = 5.991) interprets that ABO allele frequencies exist in Hardy-Weinberg equilibrium in all races. However, high magnitude of χ2 in M (5.463) signifies continued admixture in the M genetic population or the population is less stable than C and I. C and I are in more stabilized condition in this regard that might be because of closed breeding within them.Conclusion: Results of this study might be useful to blood transfusion services in Malaysia apart from human population geneticists.
format Non-Indexed Article
author Md. Ruhul Amin
Dwi Susanto
Laila Naher
spellingShingle Md. Ruhul Amin
Dwi Susanto
Laila Naher
Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
author_facet Md. Ruhul Amin
Dwi Susanto
Laila Naher
author_sort Md. Ruhul Amin
title Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
title_short Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
title_full Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
title_fullStr Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
title_full_unstemmed Distribution pattern of ABO and RH blood groups and their allelic frequencies among different ethnic groups in Malaysia
title_sort distribution pattern of abo and rh blood groups and their allelic frequencies among different ethnic groups in malaysia
publishDate 2015
url http://discol.umk.edu.my/id/eprint/8100/
https://www.pmindexing.com/journals/index.php/AJMS/article/view/575
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