Self-assembled insulin and nanogels polyelectrolyte complex (Ins/NGs-PEC) for oral insulin delivery: Characterization, lyophilization and in-vivo evaluation

Self-assembled insulin and nanogels polyelectrolyte complex (Ins/NGs-PEC) for oral insulin delivery: Characterization, lyophilization and in-vivo evaluation

Introduction: Insulin is given by injection, because when administered orally, it would be destroyed by enzymes in the digestive system, hence only about 0.1% reaches blood circulation. The purpose of the present study was to use pH sensitive polyelectrolyte methyl methacrylate (MMA)/itaconic acid (...

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Bibliographic Details
Main Authors: Mudassir, Jahanzeb, Yusrida, Darwis, Suriani, Muhamad, Khan, Arshad Ali
Format: Article
Language:English
Published: Dovepress 2019
Subjects:
R Medicine (General)
RM Therapeutics. Pharmacology
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/27329/1/Self-assembled%20insulin%20and%20nanogels%20polyelectrolyte%20complex.pdf
http://umpir.ump.edu.my/id/eprint/27329/
https://doi.org/10.2147/IJN.S199507
https://doi.org/10.2147/IJN.S199507
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Institution: Universiti Malaysia Pahang
Language: English

Internet

http://umpir.ump.edu.my/id/eprint/27329/1/Self-assembled%20insulin%20and%20nanogels%20polyelectrolyte%20complex.pdf
http://umpir.ump.edu.my/id/eprint/27329/
https://doi.org/10.2147/IJN.S199507
https://doi.org/10.2147/IJN.S199507

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