Lyophilized hybrid nanostructured lipid carriers to enhance the cellular uptake of verapamil: statistical optimization and in vitro evaluation
Verapamil is a calcium channel blocker and highly effective in the treatment of hypertension, angina pectoris, and other diseases. However, the drug has a low bioavailability of 20 to 35% due to the first pass effect. The main objective of this study was to develop hybrid verapamil-dextran nanostruc...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Open
2018
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/29850/1/Lyophilized%20hybrid%20nanostructured%20lipid%20carriers%20to%20enhance%20the%20cellular.pdf http://umpir.ump.edu.my/id/eprint/29850/ https://doi.org/10.1186/s11671-018-2744-6 https://doi.org/10.1186/s11671-018-2744-6 |
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| Institution: | Universiti Malaysia Pahang |
| Language: | English |