Needleless Electrospun Nanofibers for Drug Delivery Systems

• Main Authors: Jolius, Gimbun, Ramakrishnan, Ramprasath, Ramakrishnan, Praveen, Ranganathan, Balu
• Other Authors: Praveen, K.M.
• Format: Book Section
• Language: English
• Published: CRC Press 2022
• Subjects: RS Pharmacy and materia medica; TP Chemical technology
• Online Access: http://umpir.ump.edu.my/id/eprint/35005/2/Needleless%20Electrospun%20Nanofibers%20for%20Drug%20Delivery%20Systems.pdf; http://umpir.ump.edu.my/id/eprint/35005/; https://dx.doi.org/10.1201/9781003225577-6; https://dx.doi.org/10.1201/9781003225577-6
• Institution: Universiti Malaysia Pahang

Bubble, hollow tube, roller, wire-based and slit-surface needleless electrospinning units are discussed on the basis of the entrepreneurial product cycle of prototype development translating into commercial units. The controlled release of curcumin from a scaffold under physiological simulated conditions shows a significant release of curcumin within 48 hours of test. This work may serve as a useful guide for a drug delivery industry to process nanofibers at a large and continuous scale with a blend of drugs in the nanofibers using wire electrode electrospinning. This work may also serve as a useful guide to obtain a high-quality nanofiber from a needleless electrospinning process for drug delivery applications.