New cembrane-type diterpenoids from Bornean soft coral N ephthea sp. with antifungal activity against Lagenidium thermophilum

Three new cembrane diterpenes, nephthecrassocolides A-B (1–2) and 6-acetoxy nephthenol acetate (3) along with three known compounds, 6-acetoxy-7,8-epoxy nephthenol acetate (4), epoxy nephthenol acetate (5) and nephthenol (6) were isolated from one population of Nephthea sp. Their structures were elu...

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Bibliographic Details
Main Authors: Kazuka Tani, Takashi Kamada, Phan, Chin Soon, Charles Santhanaraju Vairappan
Format: Article
Language:English
Published: Taylor & Francis 2019
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Online Access:https://eprints.ums.edu.my/id/eprint/25480/1/New%20cembrane-type%20diterpenoids%20from%20Bornean%20soft%20coral%C2%A0Nephthea%C2%A0sp.%20with%20antifungal%20activity%20against%C2%A0Lagenidium%20thermophilum.pdf
https://eprints.ums.edu.my/id/eprint/25480/
https://doi.org/10.1080/14786419.2018.1475387
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Institution: Universiti Malaysia Sabah
Language: English
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Summary:Three new cembrane diterpenes, nephthecrassocolides A-B (1–2) and 6-acetoxy nephthenol acetate (3) along with three known compounds, 6-acetoxy-7,8-epoxy nephthenol acetate (4), epoxy nephthenol acetate (5) and nephthenol (6) were isolated from one population of Nephthea sp. Their structures were elucidated based on spectroscopic data analysis and the antifungal activities of compounds 1–6 were evaluated.