Molecular determinants of artemisinin resistance in k13 gene of plasmodium falciparum

• Main Authors: Zaw Lin, Myo Thura Zaw
• Format: Article
• Language: English; English
• Published: SCIENCEDOMAIN International 2015
• Subjects: Q Science (General); RA Public aspects of medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/27548/1/Molecular%20determinants%20of%20artemisinin%20resistance%20in%20k13%20gene%20of%20plasmodium%20falciparum%20FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/27548/2/Molecular%20determinants%20of%20artemisinin%20resistance%20in%20k13%20gene%20of%20plasmodium%20falciparum%20ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/27548/; https://www.journalmrji.com/index.php/MRJI/article/view/5697/10122
• Institution: Universiti Malaysia Sabah

Artemisinin-based combination therapy (ACT) is the first-line therapy in most malaria endemic countries. An impressive 47% reduction in the global mortality rate between 2000 and 2013 has been achieved by ACT and artemisinin (ART) monotherapy. However, artemisinin resistance (AR) by Plasmodium falci...