A mini review on emerging targets and approaches for the synthesis of anti-viral compounds- in perspective to covid-19

• Main Authors: Maheswara Rao Gokada, Pasupuleti Visweswara Rao, Hari Babu Bollikolla
• Format: Article
• Language: English
• Published: Bentham Science Publishers B.V. 2021
• Subjects: RA643-645 Disease (Communicable and noninfectious) and public health
• Online Access: https://eprints.ums.edu.my/id/eprint/30325/1/A%20mini%20review%20on%20emerging%20targets%20and%20approaches%20for%20the%20synthesis%20of%20anti-viral%20compounds-%20in%20perspective%20to%20covid-19%20ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/30325/; https://www.ingentaconnect.com/content/ben/mrmc/2021/00000021/00000010/art00004; https://doi.org/10.2174/1389557521666210104165733
• Institution: Universiti Malaysia Sabah

The novel Coronavirus disease (COVID-19) is an epidemic disease that appeared at the end of the year 2019 with a sudden increase in number and came to be considered as a pandemic disease caused by a viral infection which has threatened most countries for an emergency search for new anti-SARS-COV drugs /vaccines. At present, the number of clinical trials is ongoing worldwide on different drugs i.e. Hydroxychloroquine, Remedisvir, Favipiravir that utilize various mechanisms of action. A few countries are currently processing clinical trials, which may result in a positive outcome. Favipiravir (FPV) represents one of the feasible treatment options for COVID-19, if the result of the trials turns out positive. Favipiravir will be one of the developed possibly authoritative drugs to warrant benefits to mankind with large-scale production to meet the demands of the current pandemic Covid-19 outbreak and future epidemic outbreaks. In this review, the authors tried to explore key molecules, which will be supportive for devising COVID-19 research.