Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases

Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA and its derivatives have been used for many centuries due to their natural healing and medicinal properties. CA possesses various biological and pharmacological activities, including antioxidant, anti-inflam...

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Main Authors: Manzar Alam, Sarfraz Ahmed, Abdelbaset Mohamed Elasbal, Mohd Adnan, Shoaib Alam, Md. Imtaiyaz Hassan, Pasupuleti Visweswara Rao
Format: Article
Language:English
English
Published: Frontiers Media SA 2022
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Online Access:https://eprints.ums.edu.my/id/eprint/33349/1/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases.pdf
https://eprints.ums.edu.my/id/eprint/33349/2/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases1.pdf
https://eprints.ums.edu.my/id/eprint/33349/
https://www.frontiersin.org/articles/10.3389/fonc.2022.860508/full
https://doi.org/10.3389/fonc.2022.860508
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Institution: Universiti Malaysia Sabah
Language: English
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id my.ums.eprints.33349
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spelling my.ums.eprints.333492022-07-17T02:54:24Z https://eprints.ums.edu.my/id/eprint/33349/ Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases Manzar Alam Sarfraz Ahmed Abdelbaset Mohamed Elasbal Mohd Adnan Shoaib Alam Md. Imtaiyaz Hassan Pasupuleti Visweswara Rao RC648-665 Diseases of the endocrine glands. Clinical endocrinology Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA and its derivatives have been used for many centuries due to their natural healing and medicinal properties. CA possesses various biological and pharmacological activities, including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects. The potential therapeutic effects of CA are mediated via repression and inhibition of transcription and growth factors. CA possesses potential anticancer and neuroprotective effects in human cell cultures and animal models. However, the biomolecular interactions and pathways of CA have been described highlighting the target binding proteins and signaling molecules. The current review focuses on CA’s chemical, physical, and pharmacological properties, including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects. We further described CA’s characteristics and therapeutic potential and its future directions. Frontiers Media SA 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/33349/1/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases.pdf text en https://eprints.ums.edu.my/id/eprint/33349/2/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases1.pdf Manzar Alam and Sarfraz Ahmed and Abdelbaset Mohamed Elasbal and Mohd Adnan and Shoaib Alam and Md. Imtaiyaz Hassan and Pasupuleti Visweswara Rao (2022) Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases. Frontiers in Oncology, 12. pp. 1-18. ISSN 2234 943X https://www.frontiersin.org/articles/10.3389/fonc.2022.860508/full https://doi.org/10.3389/fonc.2022.860508
institution Universiti Malaysia Sabah
building UMS Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Sabah
content_source UMS Institutional Repository
url_provider http://eprints.ums.edu.my/
language English
English
topic RC648-665 Diseases of the endocrine glands. Clinical endocrinology
spellingShingle RC648-665 Diseases of the endocrine glands. Clinical endocrinology
Manzar Alam
Sarfraz Ahmed
Abdelbaset Mohamed Elasbal
Mohd Adnan
Shoaib Alam
Md. Imtaiyaz Hassan
Pasupuleti Visweswara Rao
Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
description Caffeic acid (CA) is found abundantly in fruits, vegetables, tea, coffee, oils, and more. CA and its derivatives have been used for many centuries due to their natural healing and medicinal properties. CA possesses various biological and pharmacological activities, including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects. The potential therapeutic effects of CA are mediated via repression and inhibition of transcription and growth factors. CA possesses potential anticancer and neuroprotective effects in human cell cultures and animal models. However, the biomolecular interactions and pathways of CA have been described highlighting the target binding proteins and signaling molecules. The current review focuses on CA’s chemical, physical, and pharmacological properties, including antioxidant, anti-inflammatory, anticancer, and neuroprotective effects. We further described CA’s characteristics and therapeutic potential and its future directions.
format Article
author Manzar Alam
Sarfraz Ahmed
Abdelbaset Mohamed Elasbal
Mohd Adnan
Shoaib Alam
Md. Imtaiyaz Hassan
Pasupuleti Visweswara Rao
author_facet Manzar Alam
Sarfraz Ahmed
Abdelbaset Mohamed Elasbal
Mohd Adnan
Shoaib Alam
Md. Imtaiyaz Hassan
Pasupuleti Visweswara Rao
author_sort Manzar Alam
title Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
title_short Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
title_full Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
title_fullStr Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
title_full_unstemmed Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
title_sort therapeutic implications of caffeic acid in cancer and neurological diseases
publisher Frontiers Media SA
publishDate 2022
url https://eprints.ums.edu.my/id/eprint/33349/1/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases.pdf
https://eprints.ums.edu.my/id/eprint/33349/2/Therapeutic%20Implications%20of%20Caffeic%20Acid%20in%20Cancer%20and%20Neurological%20Diseases1.pdf
https://eprints.ums.edu.my/id/eprint/33349/
https://www.frontiersin.org/articles/10.3389/fonc.2022.860508/full
https://doi.org/10.3389/fonc.2022.860508
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