Autophagy and EMT in cancer and metastasis: Who controls whom?

• Main Authors: Rohit Gundamaraju, Wenying Lu, Manash K. Paul, Niraj Kumar Jha, Piyush Kumar Gupta, Shreesh Ojha, Indranil Chattopadhyay, Pasupuleti Visweswara Rao, Saeid Ghavami
• Format: Article
• Language: English; English
• Published: Elsevier B.V. 2022
• Subjects: RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
• Online Access: https://eprints.ums.edu.my/id/eprint/33498/1/Autophagy%20and%20EMT%20in%20cancer%20and%20metastasis%2C%20Who%20controls%20whom.ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/33498/2/Autophagy%20and%20EMT%20in%20cancer%20and%20metastasis%2C%20Who%20controls%20whom.pdf; https://eprints.ums.edu.my/id/eprint/33498/; https://www.sciencedirect.com/science/article/abs/pii/S0925443922001016; https://doi.org/10.1016/j.bbadis.2022.166431
• Institution: Universiti Malaysia Sabah

Metastasis consists of hallmark events, including Epithelial-Mesenchymal Transition (EMT), angiogenesis, initiation of inflammatory tumor microenvironment, and malfunctions in apoptosis. Autophagy is known to play a pivotal role in the metastatic process. Autophagy has pulled researchers towards it...