Mechanisms of natural extracts of Andrographis paniculata that target lipid-dependent cancer pathways: A view from the signaling pathway

• Main Authors: Ruth Naomi, Hasnah Bahari, Ong, Zhi Yi, Keong, Yong Yoke, Hashim Embong, Retnagowri Rajandram, Teoh, Soo Huat, Fezah Othman, Rosnani Hasham, Yin, Khoo Boon, Priyatharisni Kaniappan, Muhammad Dain Yazid, Zainul Amiruddin Zakaria
• Format: Article
• Language: English; English
• Published: Multidisciplinary Digital Publishing Institute (MDPI) 2022
• Subjects: QK1-989 Botany; RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens
• Online Access: https://eprints.ums.edu.my/id/eprint/34116/2/Mechanisms%20of%20natural%20extracts%20of%20Andrographis%20paniculata%20that%20target%20lipid-dependent%20cancer%20pathways_%20A%20view%20from%20the%20signaling%20pathway.pdf; https://eprints.ums.edu.my/id/eprint/34116/3/Mechanisms%20of%20natural%20extracts%20of%20Andrographis%20paniculata%20that%20target%20lipid-dependent%20cancer%20pathways_%20A%20view%20from%20the%20signaling%20pathway%20_ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/34116/; https://www.mdpi.com/1422-0067/23/11/5972/htm; https://doi.org/10.3390/ijms23115972
• Institution: Universiti Malaysia Sabah

Andrographis paniculata is a local medicinal plant that is widely cultivated in Malaysia. It is comprised of numerous bioactive compounds that can be isolated using water, ethanol or methanol. Among these compounds, andrographolide has been found to be the major compound and it exhibits varieties of...