Recent advances on copper-catalyzed asymmetric synthesis and potential biological applications

• Main Authors: Hoorub Ahmad, Muhammad Bilal, Tahir Maqbool, Nasir Rasool, Syed Adnan Ali Shah, Zainul Amiruddin Zakaria
• Format: Article
• Language: English; English
• Published: Elsevier B.V. 2023
• Subjects: QD450-801 Physical and theoretical chemistry; RM300-666 Drugs and their actions
• Online Access: https://eprints.ums.edu.my/id/eprint/38243/1/ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/38243/2/FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/38243/; https://doi.org/10.1016/j.jscs.2023.101658
• Institution: Universiti Malaysia Sabah

An asymmetric catalysis is a form of catalytic reaction wherein a chiral catalyst controls the production of a chiral molecule to favour the synthesis of one stereoisomer over another. It’s a good way to make stereoisomeric molecules for pharmacological purposes. Among the transition metals, copper is a cost-effective, plentiful, and less poisonous metal. This review focused on the asymmetric transformations in the last fifteen years.