Potential anticancer agents identification of Hystrix brachyura bezoar through gas chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking analyses

• Main Authors: Al'aina Yuhainis Firus Khan, Ridhwan Abdul Wahab, Qamar Uddin Ahmed, Alfi Khatib, Zalikha Ibrahim, Tanzina Sharmin Nipun, Hapizah Nawawi, Syed Najmul Hejaz Azmi, Md. Zaidul Islam Sarker, Zainul Amiruddin Zakaria, Saad Alkahtani, Abdullah A. AlKahtane
• Format: Article
• Language: English; English
• Published: Elsevier 2023
• Subjects: QD450-801 Physical and theoretical chemistry; RA1-1270 Public aspects of medicine
• Online Access: https://eprints.ums.edu.my/id/eprint/38601/1/ABSTRACT.pdf; https://eprints.ums.edu.my/id/eprint/38601/2/FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/38601/; https://doi.org/10.1016/j.jksus.2023.102727
• Institution: Universiti Malaysia Sabah

Background: Bezoar (PB) is a rare, solidified form of undigested food commonly found in the gastrointestinal tract of porcupine (Hystrix brachyura). It is believed to be traditionally used to treat various diseases including different kinds of cancers in Malaysia. However, its active principles have...