Anti-metastatic and anti-angiogenic effects of curcumin analog DK1 on human osteosarcoma cells in vitro

• Main Authors: Muhammad Nazirul Mubin Aziz, Nurul Fattin Che Rahim, Yazmin Hussin, Yeap, Swee Keong, Mas Jaffri Masarudin, Nurul Elyani Mohamad, Muhammad Nadeem Akhtar, Mohd Azuraidi Osman, Cheah, Yoke Kqueen, Noorjahan Banu Alitheen
• Format: Article
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2021
• Subjects: Q1-390 Science (General); QH705-705.5 Economic biology
• Online Access: https://eprints.ums.edu.my/id/eprint/42441/1/FULL%20TEXT.pdf; https://eprints.ums.edu.my/id/eprint/42441/; https://doi.org/10.3390/ph14060532
• Institution: Universiti Malaysia Sabah

Osteosarcoma (OS) is a life-threatening malignant bone tumor associated with poor prognosis among children. The survival rate of the patient is still arguably low even with intensive treatment provided, plus with the inherent side effects from the chemotherapy, which gives more unfavorable outcomes....