The C-F bond as a conformational probe in agonist receptor interactions

Chapter 1 gives an introduction on the physical and electronic properties of fluorine and the C-F bond. The application of fluorine in organic chemistry, which is mainly attributed to the electronic properties of fluorine is described. The role of fluorine in neuropsychiatric drug development and f...

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Bibliographic Details
Main Author: Poh, Wai Chia
Format: Thesis
Language:English
Published: Scotland : University of St Andrews 2012
Subjects:
Online Access:http://hdl.handle.net/123456789/1969
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Institution: Universiti Malaysia Terengganu
Language: English
Description
Summary:Chapter 1 gives an introduction on the physical and electronic properties of fluorine and the C-F bond. The application of fluorine in organic chemistry, which is mainly attributed to the electronic properties of fluorine is described. The role of fluorine in neuropsychiatric drug development and for influencing the conformational study of bioactive amines is also illustrated.