Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2

Haemorrhagic septicaemia (HS), an economically important disease of cattle and buffaloes, is caused by Pasteurella multocida B:2. Vaccination against this disease is widely practiced but the protection was unclear. In order to improve the protection effectiveness of the vaccines, the causative or...

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Main Author: Ina Salwany, Md Yasin
Format: Thesis
Language:English
Published: Fakulti Sains dan Teknologi 2011
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Online Access:http://hdl.handle.net/123456789/670
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Institution: Universiti Malaysia Terengganu
Language: English
id my.umt.ir-670
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spelling my.umt.ir-6702016-03-10T08:53:04Z Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2 Ina Salwany, Md Yasin QR 82 .P25 I5 2009 Ina Salwany Md Yasin Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2 Pasteurella multocida Haemorrhagic septicaemia (HS), an economically important disease of cattle and buffaloes, is caused by Pasteurella multocida B:2. Vaccination against this disease is widely practiced but the protection was unclear. In order to improve the protection effectiveness of the vaccines, the causative organism has been fractionated and the various cell surface components were studied. The fimbrial proteins are particularly attractive candidate for development of recombinant vaccine because they are strong immunogens. This study was conducted to characterize and determine the antigenicity of the fimbrial protein of Pasteurella multocida B:2, followed by development of recombinant cell vaccine expressing the fimbrial protein. The study also was carried out on the potential and efficacy of Pasteurella multocida B:2 recombinant fimbrial proteins in the production of vaccine against haemorrhagic septicaemia. 2011-02-21T07:20:01Z 2011-02-21T07:20:01Z 2009-06 Thesis http://hdl.handle.net/123456789/670 en application/pdf application/pdf Fakulti Sains dan Teknologi
institution Universiti Malaysia Terengganu
building Perpustakaan Sultanah Nur Zahirah
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaysia Terengganu
content_source UMT-IR
url_provider http://umt-ir.umt.edu.my:8080/
language English
topic QR 82 .P25 I5 2009
Ina Salwany Md Yasin
Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
Pasteurella multocida
spellingShingle QR 82 .P25 I5 2009
Ina Salwany Md Yasin
Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
Pasteurella multocida
Ina Salwany, Md Yasin
Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
description Haemorrhagic septicaemia (HS), an economically important disease of cattle and buffaloes, is caused by Pasteurella multocida B:2. Vaccination against this disease is widely practiced but the protection was unclear. In order to improve the protection effectiveness of the vaccines, the causative organism has been fractionated and the various cell surface components were studied. The fimbrial proteins are particularly attractive candidate for development of recombinant vaccine because they are strong immunogens. This study was conducted to characterize and determine the antigenicity of the fimbrial protein of Pasteurella multocida B:2, followed by development of recombinant cell vaccine expressing the fimbrial protein. The study also was carried out on the potential and efficacy of Pasteurella multocida B:2 recombinant fimbrial proteins in the production of vaccine against haemorrhagic septicaemia.
format Thesis
author Ina Salwany, Md Yasin
author_facet Ina Salwany, Md Yasin
author_sort Ina Salwany, Md Yasin
title Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
title_short Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
title_full Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
title_fullStr Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
title_full_unstemmed Identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida B:2
title_sort identification, cloning, sequencing, expression and protective capacity of the gene encoding a fimbrial protien of pasteurella multocida b:2
publisher Fakulti Sains dan Teknologi
publishDate 2011
url http://hdl.handle.net/123456789/670
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