A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer
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| Language: | English |
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2011
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| Online Access: | http://dspace.unimap.edu.my/xmlui/handle/123456789/15089 |
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| Institution: | Universiti Malaysia Perlis |
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my.unimap-150892011-10-27T06:41:39Z A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer Ahmad Faizal, Salleh Muhammad Izham, Ismail Md Tasyrif, Abdul Rahman Sazali, Yaacob, Prof. Dr. Khaled, Helmy, Dr. ahmadfaizal@unimap.edu.my Metered Dose Inhaler IPA Fan Computational fluid dynamics Spacer Link to publisher's homepage at http://www.springerlink.com/ Metered Dose Inhalers (MDI) is used to prevent and relieve the symptoms and progression of certain diseases (asthma, chronic obstructive pulmonary disease, cystic fibrosis and bronchiectosis) by delivering the inhaled pharmaceutical aerosols (IPA) to the desired area. The MDI is easily can be placed in a pocket or purse and ready to be used instantly and these are reasons why it is used widely. The spacer was used to avoid deposition of most IPA on the mouth throat area whereby it promotes the expansion and mixing of the IPA before it is inhaled. However, the IPA inhaling efficiency using MDI is relatively low compare to other methods. A study on the effect of various motor rotational speeds was carried out to understand their effect on the IPA fluid dynamics characteristics. The Computational Fluid Dynamics (CFD) software was used to analyze the IPA flow pattern inside the spacer. The results show that the higher motor RPM will give a better delivery of the IPA through MDI spacer. 2011-10-27T06:41:39Z 2011-10-27T06:41:39Z 2008-06-25 Working Paper IFMBE Proceedings, vol. 21 (1), 2008, pages 653-656 978-3-5406-9138-9 1680-0737 http://www.springerlink.com/content/j2228768687r4135/fulltext.pdf http://hdl.handle.net/123456789/15089 en Proceedings of the 4th Kuala Lumpur International Conference on Biomedical Engineering 2008 Springerlink |
| institution |
Universiti Malaysia Perlis |
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UniMAP Library |
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| continent |
Asia |
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Malaysia |
| content_provider |
Universiti Malaysia Perlis |
| content_source |
UniMAP Library Digital Repository |
| url_provider |
http://dspace.unimap.edu.my/ |
| language |
English |
| topic |
Metered Dose Inhaler IPA Fan Computational fluid dynamics Spacer |
| spellingShingle |
Metered Dose Inhaler IPA Fan Computational fluid dynamics Spacer Ahmad Faizal, Salleh Muhammad Izham, Ismail Md Tasyrif, Abdul Rahman Sazali, Yaacob, Prof. Dr. Khaled, Helmy, Dr. A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| description |
Link to publisher's homepage at http://www.springerlink.com/ |
| author2 |
ahmadfaizal@unimap.edu.my |
| author_facet |
ahmadfaizal@unimap.edu.my Ahmad Faizal, Salleh Muhammad Izham, Ismail Md Tasyrif, Abdul Rahman Sazali, Yaacob, Prof. Dr. Khaled, Helmy, Dr. |
| format |
Working Paper |
| author |
Ahmad Faizal, Salleh Muhammad Izham, Ismail Md Tasyrif, Abdul Rahman Sazali, Yaacob, Prof. Dr. Khaled, Helmy, Dr. |
| author_sort |
Ahmad Faizal, Salleh |
| title |
A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| title_short |
A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| title_full |
A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| title_fullStr |
A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| title_full_unstemmed |
A preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| title_sort |
preliminary study of inhaled pharmaceutical aerosol flow characteristics in metered dose inhaler spacer |
| publisher |
Springerlink |
| publishDate |
2011 |
| url |
http://dspace.unimap.edu.my/xmlui/handle/123456789/15089 |
| _version_ |
1643790936908496896 |