Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage

Access is limited to UniMAP community.

Saved in:

Bibliographic Details
Main Author:	Taufiq Aminullah, Mokhtar
Other Authors:	Dr. Midhat Nabil Ahmad Salimi
Format:	Learning Object
Language:	English
Published:	Universiti Malaysia Perlis (UniMAP) 2013
Subjects:	Hydroxyapatite (HAp) Hydroxyapatite (HAp) Nanoparticle Human bone Enamel Bioactive material Biomedical
Online Access:	http://dspace.unimap.edu.my/xmlui/handle/123456789/27691
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	Universiti Malaysia Perlis
Language:	English

id	my.unimap-27691
record_format	dspace
spelling	my.unimap-276912013-08-27T01:15:10Z Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage Taufiq Aminullah, Mokhtar Dr. Midhat Nabil Ahmad Salimi Hydroxyapatite (HAp) Hydroxyapatite (HAp) Nanoparticle Human bone Enamel Bioactive material Biomedical Access is limited to UniMAP community. Hydroxyapatite, (HAp), Ca10(PO4)6(OH)2, is a physically occurring mineral found in the inorganic component of human bone and enamel. The basic elements of HAp are mainly calcium and phosphorous, with a stoichiometric calcium to phosphorous ratio of 1.67 capable of promoting intimate bone growth onto femoral implants. HAp is rendered a bioactive material since it has the ability to promote such growth with rapid fixation in what is also considered an osteoconductive process. The present study aims to produce HAp powders via the wet chemical precipitation technique, in order to evaluate the critical process parameters (mixing temperature, stirring rate, and Ca/P molar ratio) and their effect (main and interaction) on controlling the final HAp powder characteristics, such as, phase composition, crystallinity, crystallite size and particle size. 48.052 nm of HAp crystallite size was produced at 0.60 Ca/P molar ratio, 200 rpm of stirring rate and 600°C of mixing temperature. These powders were synthesised with a view to satisfying regulatory requirements which is favaourable particle size for biomedical usage is for the smallest particle as possible which is in this study the particle size should be in range of 30-50nm. These effects were quantified using Design of Experiments (Design Expert) to develop mathematical models, in terms of the chemical precipitation process parameters. The HAp nanoparticles were also analyzed by using Fourier Transform Infrared (FTIR), X-ray Diffractometer (XRD) and Scanning Electron Microscope (SEM). 2013-08-27T01:15:10Z 2013-08-27T01:15:10Z 2012-06 Learning Object http://hdl.handle.net/123456789/27691 en Universiti Malaysia Perlis (UniMAP) School of Bioprocess Engineering
institution	Universiti Malaysia Perlis
building	UniMAP Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Perlis
content_source	UniMAP Library Digital Repository
url_provider	http://dspace.unimap.edu.my/
language	English
topic	Hydroxyapatite (HAp) Hydroxyapatite (HAp) Nanoparticle Human bone Enamel Bioactive material Biomedical
spellingShingle	Hydroxyapatite (HAp) Hydroxyapatite (HAp) Nanoparticle Human bone Enamel Bioactive material Biomedical Taufiq Aminullah, Mokhtar Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
description	Access is limited to UniMAP community.
author2	Dr. Midhat Nabil Ahmad Salimi
author_facet	Dr. Midhat Nabil Ahmad Salimi Taufiq Aminullah, Mokhtar
format	Learning Object
author	Taufiq Aminullah, Mokhtar
author_sort	Taufiq Aminullah, Mokhtar
title	Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_short	Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_full	Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_fullStr	Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_full_unstemmed	Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage
title_sort	production of hydroxyapatite (hap) nanoparticles by wet chemistry methods for biomedical usage
publisher	Universiti Malaysia Perlis (UniMAP)
publishDate	2013
url	http://dspace.unimap.edu.my/xmlui/handle/123456789/27691
_version_	1643795455706923008

Production of Hydroxyapatite (HAp) Nanoparticles by wet chemistry methods for biomedical usage

Similar Items