Synthesis and characterisation of hydrogel based composites for bone regeneration

The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malays...

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Main Authors:	Killion, John, Gonzalez, Nelly, Geever, Luke, Devine, Declan, Kennedy, James, Higginbotham, Clement L.
Other Authors:	jkillion@research.ait.ie
Format:	Working Paper
Language:	English
Published:	Universiti Malaysia Perlis (UniMAP) 2013
Subjects:	Hydroxyapatite Polyethylene glycol Mechanical properties
Online Access:	http://dspace.unimap.edu.my/xmlui/handle/123456789/27877
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Institution:	Universiti Malaysia Perlis
Language:	English

id	my.unimap-27877
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spelling	my.unimap-278772017-11-29T06:50:35Z Synthesis and characterisation of hydrogel based composites for bone regeneration Killion, John Gonzalez, Nelly Geever, Luke Devine, Declan Kennedy, James Higginbotham, Clement L. jkillion@research.ait.ie magargo7@etsid.upv.es Hydroxyapatite Polyethylene glycol Mechanical properties The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia. The current gold standard treatment for bone defects are biological grafts. Due to the inherent disadvantages for these biological grafts, a new synthetic alternative are being sought. Tissue engineering has shown great potential to replace the current treatments, due to its ability to provide structural support to the defect while promoting cellular attachment, proliferation and migration to help the formation new bone tissue. In this study, novel biocomposites of polyethylene glycol dimethacrylate (PEGDMA) and hydroxyapatite (HaP) were prepared via photopolymerisation. The objective of this study was to understand the effects of varying hydroxyapatite concentration had on the mechanical and thermal properties of the resultant biocomposite. The prepared hydrogel based composites were characterised by compression testing, gel fraction, differential scanning calorimetry (DSC) and swelling studies. Compression strength were tailored by very hydroxyapatite concentration (5 wt%-17.5 wt%). For example, variation in HaP concentration (A0-A17.5) resulted in an increase in Young’s modulus from 5.41 MPa to 5.89 MPa. 2013-09-03T02:10:49Z 2013-09-03T02:10:49Z 2012-06-18 Working Paper p. 1-8 978-967-5760-11-2 http://hdl.handle.net/123456789/27877 en Proceedings of the The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012); Universiti Malaysia Perlis (UniMAP)
institution	Universiti Malaysia Perlis
building	UniMAP Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Perlis
content_source	UniMAP Library Digital Repository
url_provider	http://dspace.unimap.edu.my/
language	English
topic	Hydroxyapatite Polyethylene glycol Mechanical properties
spellingShingle	Hydroxyapatite Polyethylene glycol Mechanical properties Killion, John Gonzalez, Nelly Geever, Luke Devine, Declan Kennedy, James Higginbotham, Clement L. Synthesis and characterisation of hydrogel based composites for bone regeneration
description	The 2nd International Malaysia-Ireland Joint Symposium on Engineering, Science and Business 2012 (IMiEJS2012) jointly organized by Universiti Malaysia Perlis and Athlone Institute of Technology in collaboration with The Ministry of Higher Education (MOHE) Malaysia, Education Malaysia and Malaysia Postgraduates Student Association Ireland (MyPSI), 18th - 19th June 2012 at Putra World Trade Center (PWTC), Kuala Lumpur, Malaysia.
author2	jkillion@research.ait.ie
author_facet	jkillion@research.ait.ie Killion, John Gonzalez, Nelly Geever, Luke Devine, Declan Kennedy, James Higginbotham, Clement L.
format	Working Paper
author	Killion, John Gonzalez, Nelly Geever, Luke Devine, Declan Kennedy, James Higginbotham, Clement L.
author_sort	Killion, John
title	Synthesis and characterisation of hydrogel based composites for bone regeneration
title_short	Synthesis and characterisation of hydrogel based composites for bone regeneration
title_full	Synthesis and characterisation of hydrogel based composites for bone regeneration
title_fullStr	Synthesis and characterisation of hydrogel based composites for bone regeneration
title_full_unstemmed	Synthesis and characterisation of hydrogel based composites for bone regeneration
title_sort	synthesis and characterisation of hydrogel based composites for bone regeneration
publisher	Universiti Malaysia Perlis (UniMAP)
publishDate	2013
url	http://dspace.unimap.edu.my/xmlui/handle/123456789/27877
_version_	1643802735713189888

Synthesis and characterisation of hydrogel based composites for bone regeneration

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