The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria
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2014
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my.unimap-335692014-04-09T17:07:21Z The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria Shwe, Tin Myint, Pe Than Mohammad Iqbal, Omar@Ye Htut, Assoc. Prof. Dr. Myint, Win Soe, Lin iqbalomar@unimap.edu.my Plasmodium falciparum malaria Cerebral signs Mefloquine-artemether Drug therapy Link to publisher's homepage at http://www.sciencedirect.com/ 30 pairs of patients with complicated Plasmodium falciparum malaria (with anaemia, hyperpyrexia, jaundice or more than 5% of erythrocytes parasitized) were studied. Patients with cerebral signs and symptoms were excluded. One group of patients was treated with oral mefloquine (750 mg) and artemether (600 mg by injection, 200 mg initially and 100 mg every 12 h). The second group of patients was treated with quinine (10 mg/kg orally every 8 h for 7 d). All patients were admitted to hospital for 7 d and examined subsequently on days 14, 21 and 28. All those treated with mefloquine plus artemether survived and their parasite clearance time and fever clearance time were significantly shorter than those of patients receiving quinine. 2 patients treated with quinine died. There was no recrudescence in any patient of either group. 2014-04-09T17:07:21Z 2014-04-09T17:07:21Z 1988 Article Transactions of the Royal Society of Tropical Medicine and Hygiene, vol. 82(5), 1988, pages 665-666 1878-3503 (Online) 0035-9203 (Print) http://dspace.unimap.edu.my:80/dspace/handle/123456789/33569 http://dx.doi.org/10.1016/0035-9203(88)90187-3 http://www.sciencedirect.com/science/article/pii/0035920388901873 en Elsevier Ltd. |
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English |
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Plasmodium falciparum malaria Cerebral signs Mefloquine-artemether Drug therapy |
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Plasmodium falciparum malaria Cerebral signs Mefloquine-artemether Drug therapy Shwe, Tin Myint, Pe Than Mohammad Iqbal, Omar@Ye Htut, Assoc. Prof. Dr. Myint, Win Soe, Lin The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| description |
Link to publisher's homepage at http://www.sciencedirect.com/ |
| author2 |
iqbalomar@unimap.edu.my |
| author_facet |
iqbalomar@unimap.edu.my Shwe, Tin Myint, Pe Than Mohammad Iqbal, Omar@Ye Htut, Assoc. Prof. Dr. Myint, Win Soe, Lin |
| format |
Article |
| author |
Shwe, Tin Myint, Pe Than Mohammad Iqbal, Omar@Ye Htut, Assoc. Prof. Dr. Myint, Win Soe, Lin |
| author_sort |
Shwe, Tin |
| title |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| title_short |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| title_full |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| title_fullStr |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| title_full_unstemmed |
The effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| title_sort |
effect of mefloquine-artemether compared with quinine on patients with complicated falciparum malaria |
| publisher |
Elsevier Ltd. |
| publishDate |
2014 |
| url |
http://dspace.unimap.edu.my:80/dspace/handle/123456789/33569 |
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1643797216247152640 |