Global Globin Network and adopting genomic variant database requirements for thalassemia

• Main Authors: Hashim, Halim-Fikri, Ninie Nadia, Zulkiplii, Hafza, Alauddin, Celestea, Bento, Carsten, W Lederer, Petros, Kountouris, Marina, Kleanthous, Yetti, Hernaningsih, Thong, Meow Keong, Muhammad Hamdi, Mahmood, Norafiza, Mohd Yasin, Ezalia, Esa, Jacques, Elion, Domenico, Coviello, Raja Zahratul Azma, Raja Sabudin, Ghada, El-Kamah, John, Burn, Narazah, Mohd Yusoff, Raj, Ramesar, Zilfalil, Alwi
• Format: Article
• Language: English
• Published: Oxford University Press 2024
• Subjects: QH426 Genetics; R Medicine (General); RB Pathology
• Online Access: http://ir.unimas.my/id/eprint/46285/1/Global%20Globin%20Network%20and%20adopting%20genomic.pdf; http://ir.unimas.my/id/eprint/46285/; https://academic.oup.com/database/article/doi/10.1093/database/baae080/7749354; https://doi.org/10.1093/database/baae080
• Institution: Universiti Malaysia Sarawak

Thalassemia is one of the most prevalent monogenic disorders in low- and middle-income countries (LMICs). There are an estimated 270 million carriers of hemoglobinopathies (abnormal hemoglobins and/or thalassemia) worldwide, necessitating global methods and solutions for effective and optimal therap...