Hb lepore/β0-thalassaemia with α+-thalassaemia interactions, a potential diagnostic pitfall

• Main Authors: Hafiza, Alauddin, Suziana, Mohamad Nasir, Madzlifah, Ahadon, Raja Zahratul Azma, Raja Azma, Azlin, Ithnin, Noor Hamidah, Hamidah, Hamidah, B. Alias, Loh, C. Khai, Zarina, Abdul-Latiff, Nor Azian, Abdul Murad, Ainoon, Othman
• Format: E-Article
• Language: English
• Published: Malaysian Society of Pathologists 2015
• Subjects: R Medicine (General); RB Pathology
• Online Access: http://ir.unimas.my/id/eprint/15206/1/Hb-lepore%CE%B2sup0sup-thalassaemia-with-%CE%B1sup%2Bsup-thalassaemia-interactions%2C-a-potential-diagnostic-pitfall_2015_Malaysian-Journal-of-Pathology.html; http://ir.unimas.my/id/eprint/15206/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-84952309035&partnerID=40&md5=b7383cba3989c0053a1c83261268b235
• Institution: Universiti Malaysia Sarawak

Haemoglobin (Hb) Lepore is a variant Hb consisting of two α-globin and two δβ-globin chains. In a heterozygote, it is associated with clinical findings of thalassaemia minor, but interactions with other haemoglobinopathies can lead to various clinical phenotypes and pose diagnostic challenges. We re...