Synthesis and characterisation of halogenated bis(acylthiourea) derivatives and its antibacterial activities

• Main Authors: Ainaa Nadiah, Abd Halim, Zainab, Ngaini
• Format: E-Article
• Published: Taylor & Francis 2017
• Subjects: Q Science (General)
• Online Access: http://ir.unimas.my/id/eprint/18505/; https://www.researchgate.net/publication/316030203
• Institution: Universiti Malaysia Sarawak

A total of 12 bis(acylthiourea) derivatives with different pharmacophores have been synthesized via nucleophilic substitution reaction of benzene-1,4-dicarbonyl isothiocyanate intermediate with aromatic amine bearing halogens at the ortho, meta and para positions. The structures of the synthesised c...