Small Cell Transformation and T790M Mutation as Coresistance Mechanisms for First-line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) Therapy Failure
Discovery of the activating EGFR mutation gene has revolutionized the treatment of patients with NSCLC. Nevertheless, resistance to first-line EGFR tyrosine kinase inhibitors (TKIs) develops in most patients with EGFR-mutant NSCLC after a period of 9 to 13 months. Here, we reported a case of fi...
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier Inc.
2017
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/19173/7/Small%20Cell.pdf http://ir.unimas.my/id/eprint/19173/ http://www.jto.org/article/S1556-0864(17)30568-3/pdf |
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| Institution: | Universiti Malaysia Sarawak |
| Language: | English |