Size controlled fabrication of cellulose nanoparticles for drug delivery applications
Spherically shaped cellulose nanoparticles with average particle diameter range between 70 and 365 nm were fabricated from cotton fibers by a simple nanoprecipitation method. The average particle diameter of cellulose nanoparticles could be precisely controlled by modulating the synthesis conditions...
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| Main Authors: | , , |
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| Format: | E-Article |
| Language: | English |
| Published: |
Editions de Sante
2018
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/19597/1/Size%20controlled%20fabrication%20of%20cellulose%20nanoparticles%20for%20drug%20delivery%20applications.pdf http://ir.unimas.my/id/eprint/19597/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032336043&doi=10.1016%2fj.jddst.2017.10.021&partnerID=40&md5=e90140038d165ef14be615351a43c593 |
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| Institution: | Universiti Malaysia Sarawak |
| Language: | English |
| Summary: | Spherically shaped cellulose nanoparticles with average particle diameter range between 70 and 365 nm were fabricated from cotton fibers by a simple nanoprecipitation method. The average particle diameter of cellulose nanoparticles could be precisely controlled by modulating the synthesis conditions such as cellulose solution concentration and volume ratio of solvent/non-solvent. Methylene blue (MB) as a model hydrophilic drug was loaded onto cellulose nanoparticles via the in-situ nanoprecipitation process. The loading efficiency and release profile of MB were observed to be affected by the average particle diameter of cellulose nanoparticles. © 2017 |
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