Topoisomerase I inhibition and cytotoxicity of 5-Bromo- and 5-Phenylterbenzimidazoles
Topoisomerase I is an enzyme that is essential for maintaining the three-dimensional structure of DNA during the processes of transcription, translation and mitosis. With the introduction of new clinical agents that are effective in poisoning topoisomerase I, this enzyme has proved to be an attracti...
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| Main Authors: | , , , , , |
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| Format: | E-Article |
| Language: | English |
| Published: |
Bioorganic & Medicinal Chemistry Letters
2000
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/2497/1/Topoisomerase%20I%20inhibition%20and%20cytotoxicity%20of%205-Bromo-%20and%205-Phenylterbenzimidazoles.pdf http://ir.unimas.my/id/eprint/2497/ |
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| Institution: | Universiti Malaysia Sarawak |
| Language: | English |