Clinical Significance of BCL2, C-MYC, and BCL6 Genetic Abnormalities, Epstein-Barr Virus Infection, CD5 Protein Expression, Germinal Center B Cell/Non-Germinal Center B-Cell Subtypes, Co-expression of MYC/BCL2 Proteins and Co-expression of MYC/BCL2/BCL6 Proteins in Diffuse Large B-Cell Lymphoma : A Clinical and Pathological Correlation Study of 120 Patients

• Main Authors: Kuan, Jew-Win, Ting, Choo Yuen, Chang, K. M., Jameela, Sathar, Chew, Lee Ping, Wong, Jacqueline Oy-Leng, Yusri, Yusuf, Lily, Wong, Ahmad Toha, Samsudin, Mohd Nurjaya, Bin Mohd Pana, Lee, Suk Kam, Raja Gopal, Navarasi S., Rita, Puri, Ong, Tee-Chuan, Samsol Kamal, Bahari, Goh, Ai-Sim, Teoh, Ching- Soon
• Format: Article
• Language: English
• Published: Ivyspring International Publisher 2019
• Subjects: R Medicine (General); RB Pathology
• Online Access: http://ir.unimas.my/id/eprint/28478/1/Choo-Yuen%20Ting.pdf; http://ir.unimas.my/id/eprint/28478/; https://www.ncbi.nlm.nih.gov/pubmed/31171907
• Institution: Universiti Malaysia Sarawak

Background: Clinical significance of germinal center B-cell (GCB) and non-GCB sub-categorization, expression of MYC, BCL2, BCL6, CD5 proteins and Epstein Barr virus encoded RNA (EBER) positivity in diffuse large B-cell lymphoma (DLBCL) remain controversial. Could these biomarkers accurately identify...