The functional -94 insertion/deletion ATTG polymorphism in the promoter region of NFKB1 gene increases the risk of sporadic colorectal cancer.

• Main Authors: Mohd Suzairi, M.S., Tan, S.C., Ahmad Aizat, Abdul Aziz, Mohd Aminudin, Mustapha, Siti Nurfatimah, Mohd Shahpudin, Andee, Z.D., Ankathil, Ravindran
• Format: Article
• Language: English
• Published: Elsevier Science, Ltd. 2013
• Subjects: Q Science (General); R Medicine (General)
• Online Access: http://ir.unimas.my/id/eprint/30234/1/The%20functional%20.pdf; http://ir.unimas.my/id/eprint/30234/; https://www.sciencedirect.com/science/article/abs/pii/S1877782113000945; https://doi.org/10.1016/j.canep.2013.05.007
• Institution: Universiti Malaysia Sarawak

Objective: To investigate the allele and genotype frequencies of NFKBI -94 ins/de! ATTG (rs28720239) polymorphism and to evaluate the association between the polymorphism and colorectal cancer (CRC) risk in Malaysian population. Methods: Genomic DNA was extracted from the peripheral blood samples of...