A preliminary study on the polymorphism of hypervariable D17S5 locus in UNIMAS Chinese population

• Main Authors: Hairul Azman, Roslan, Sim, Jessie Ann Chiew Ling, Rosmawati, Saat
• Format: Article
• Language: English
• Published: Faculty of Resource Science and Technology 2011
• Subjects: QH426 Genetics
• Online Access: http://ir.unimas.my/id/eprint/31739/1/A%20PRELIMINARY%20STUDY%20ON%20THE%20POLYMORPHISM%20OF%20HYPERARIABLE%20-%20Copy.pdf; http://ir.unimas.my/id/eprint/31739/; http://www.bjrst.unimas.my/
• Institution: Universiti Malaysia Sarawak

Variable number of tandem repeats (VNTRs) is one of the most useful tools in the study of polymorphism and have spurred studies in many populations throughout the world. Here we eport a preliminary VNTR study of the polymorphism of the hypervariable locus D17S5, in the Chinese community in UNIMAS. Samples were obtained from seventy-five unrelated Chinese individuals. The study showed the presence of six lleles ranging from 170bp to 520bp in sizes. The allele requencies ranged from 0.02 to 0.44 with heterozygosity value of 0.32. The distributions of the D17S5 alleles in the UNIMAS Chinese population were also determined with allele 2 having the ighest frequency and alleles 5 and 6 being the lowest requencies, respectively