Robust radiogenomics approach to the identification of EGFR mutations among patients with NSCLC from three different countries using topologically invariant Betti numbers

• Main Authors: Ninomiya, Kenta, Arimura, Hidetaka, Chan, Wai Yee, Tanaka, Kentaro, Mizuno, Shinichi, Nadia Fareeda, Muhammad Gowdh, Nur Adura, Yaakup, Liam, Chong Kin, Chai, Chee Shee, Ng, Kwan Hoong
• Format: Article
• Language: English
• Published: PLOS 2021
• Subjects: RC0254 Neoplasms. Tumors. Oncology (including Cancer); RZ Other systems of medicine
• Online Access: http://ir.unimas.my/id/eprint/33843/1/Chee%20Shee.pdf; http://ir.unimas.my/id/eprint/33843/; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0244354; https://doi.org/10.1371/journal. pone.0244354
• Institution: Universiti Malaysia Sarawak

Abstract Objectives: To propose a novel robust radiogenomics approach to the identification of epidermal growth factor receptor (EGFR) mutations among patients with non-small cell lung cancer (NSCLC) using Betti numbers (BNs). Materials and methods: Contrast enhanced computed tomography (CT) ima...