Identification Of Protein Partners Of The Human Nucleophosmin (Npm1) Using Bioinformatics Analysis
Nucleophosmin, NPMl can be found in the leukaemia and cancer study. In this paper, NPMl is used as a target protein to search its protein partner and the possible interaction between them. The method used is by using bioinfonnatic analysis multiple alignment, 3D modelling, model assessment, struc...
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| Main Author: | |
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| Format: | Final Year Project Report |
| Language: | English |
| Published: |
Universiti Malaysia Sarawak (UNIMAS)
2018
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| Online Access: | http://ir.unimas.my/id/eprint/35175/1/ANIS%20SABRINA%20BINTI%20JUBAIDI%20ft.pdf http://ir.unimas.my/id/eprint/35175/ |
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| Institution: | Universiti Malaysia Sarawak |
| Language: | English |
| Summary: | Nucleophosmin, NPMl can be found in the leukaemia and cancer study. In this paper,
NPMl is used as a target protein to search its protein partner and the possible interaction
between them. The method used is by using bioinfonnatic analysis multiple alignment,
3D modelling, model assessment, structure neighbour, candidate partners, and structural
docking. The tool revealed 4KZX and 4KZY as the structural neighbours and possible
candidate partners. There are around seven candidate partners of NPMI has been
discovered and the proteins that has been discovered has the same expression as the NPM I. |
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