Granulomatous inflammation in ginbuna crucian carp Carassius auratus langsdorfii against Mycobacterium gordonae

• Main Authors: Goshi, Kato, Taichi, Kakazu, Mitsuo, Yamada, Lau, Lik Ming, Kazue, Nakajima, Shoh, Sato, Teruyuki, Nakanishi, Makoto, Endo, Motohiko, Sano
• Format: Article
• Language: English
• Published: Elsevier B.V. 2019
• Subjects: SH Aquaculture. Fisheries. Angling
• Online Access: http://ir.unimas.my/id/eprint/45000/3/Granulomatous.pdf; http://ir.unimas.my/id/eprint/45000/; https://www.sciencedirect.com/science/article/abs/pii/S0145305X18304889; https://doi.org/10.1016/j.dci.2018.10.009
• Institution: Universiti Malaysia Sarawak

In this study, we investigated the immune responses against Mycobacterium gordonae in ginbuna crucian carp. Cumulative mortality of ginbuna injected with 2.0 × 10^7 CFU of M. gordonae was 50% at 170 days post-infection. CD4-1, CD8α, T-bet and IFNγ2 gene expression levels were significantly upregulat...