CD4-1 and CD4-2 single positive are two major CD4 lymphocyte subpopulations in ginbuna crucian carp Carassius auratus langsdorfii

• Main Authors: Lik Ming, Lau, Misato, Kuga, Motohiko, Sano, Goshi, Kato
• Format: Article
• Language: English
• Published: Elsevier Ltd. 2023
• Subjects: SH Aquaculture. Fisheries. Angling
• Online Access: http://ir.unimas.my/id/eprint/45206/1/CD4-1.pdf; http://ir.unimas.my/id/eprint/45206/; https://www.sciencedirect.com/science/article/abs/pii/S0145305X23011217; https://doi.org/10.1016/j.dci.2023.104968
• Institution: Universiti Malaysia Sarawak

Fish possess two divergent forms of CD4: CD4-1 resembles the mammalian CD4 whereas CD4-2 is a unique CD4 homolog. Three CD4+ cell subpopulations were identified in fish: CD4-1 single-positive (SP), CD4-2 SP, CD4-1/CD4-2 (CD4) double-positive (DP). With the aid of monoclonal antibodies (mAbs) against...