Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes
Conventionally synthesized silver nanoparticles (AgNP) imposed an alarming effect on the environment and caused toxicity to humans. However, the use of zeolite (zeoY) as a support system could increase its biocompatibility and reduce its toxicity. Hence, green synthesis of AgNP using Persicaria odor...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier B.V.
2024
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/45321/2/Biosynthesized%20Persicaria%20odorata-silver.pdf http://ir.unimas.my/id/eprint/45321/ https://www.sciencedirect.com/science/article/abs/pii/S1674200124000944 https://doi.org/10.1016/j.partic.2024.05.015 |
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| Institution: | Universiti Malaysia Sarawak |
| Language: | English |
| Summary: | Conventionally synthesized silver nanoparticles (AgNP) imposed an alarming effect on the environment and caused toxicity to humans. However, the use of zeolite (zeoY) as a support system could increase its biocompatibility and reduce its toxicity. Hence, green synthesis of AgNP using Persicaria odorata leaves extract supported on zeolite Y has been prepared by an in situ synthesis technique. The phytochemical compounds in the optimized leaf extract concentration of 1% and volume of 0.9 mL reduced the silver ions to AgNP within the zeolite Y pores. Morphological observation revealed the incorporation of AgNP in the zeolite Y (average size: 18.51 nm). The release of AgNP exhibited antibacterial activity on C. acnes at a concentration lower than 1 g L−1 which is also dependent on the electrolyte. AgNP-zeoY promoted cell proliferation in vitro and it has a non-irritating effect when tested in the in vivo skin irritation model. |
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