Facile Synthesis and Applications of Flavonoid-Heterocyclic Derivatives

• Main Authors: Saba, Farooq, Zainab, Ngaini
• Format: Article
• Language: English
• Published: Bentham Science Publishers 2024
• Subjects: QD Chemistry
• Online Access: http://ir.unimas.my/id/eprint/45939/1/140835; http://ir.unimas.my/id/eprint/45939/; https://www.eurekaselect.com/article/140835
• Institution: Universiti Malaysia Sarawak

Flavonoids belong to the polyphenol group that naturally exists in fruits, vegetables, tea, and grains. Flavonoids, as secondary metabolites, show indispensable contributions to biolog-ical processes and the responses of plants to numerous environmental factors. The bioactivity of flavonoids depends on C6-C3-C6 ring substitution patterns that exhibit bioactive antioxidant, an-timicrobial, antifungal, antitumor, and anti-inflammatory properties. The synthesis of flavonoids has been reported by various methodologies. Therefore, the present review systematically sum-marizes the synthesis of recent heterocyclic flavonoid derivatives via facile synthetic approaches since the research in flavonoids is useful for therapeutic and biotechnology fields.