Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient

glucose; insulin; adult; Article; blood glucose monitoring; critically ill patient; female; glycemic control; health care; hepatic clearance; human; insulin clearance; insulin sensitivity; intensive care unit; intensive glucose nutrition insulin model; major clinical study; Malaysia; male; renal cle...

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Main Authors: Razak N.N.A., Ahamad N., Suhaimi F., Jamaluddin U., Ralib A.M.
Other Authors: 37059587300
Format: Article
Published: Innovare Academics Sciences Pvt. Ltd 2023
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Institution: Universiti Tenaga Nasional
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spelling my.uniten.dspace-229292023-05-29T14:13:28Z Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient Razak N.N.A. Ahamad N. Suhaimi F. Jamaluddin U. Ralib A.M. 37059587300 56960410200 36247893200 55330889600 37031770900 glucose; insulin; adult; Article; blood glucose monitoring; critically ill patient; female; glycemic control; health care; hepatic clearance; human; insulin clearance; insulin sensitivity; intensive care unit; intensive glucose nutrition insulin model; major clinical study; Malaysia; male; renal clearance A clinically verified patient-specific glucose-insulin metabolic model known as ICING is used to account for time-varying insulin sensitivity. ICING was developed and validated from critically-ill patients with various medical conditions in the intensive care unit in Christchurch Hospital, New Zealand. Hence, it is interesting and vital to analyse the compatibility of the model once fitted to Malaysian critically-ill data. Results were assessed in terms of percentage of model-fit error, both by cohort and per-patient analysis. The ICING model accomplished median fitting error of <1% over data from 63 patients. Most importantly, the median per-patients is at a low fitting error of 0.34% and per cohort is 0.35%. These results provide a promising avenue for near future simulations of developing tight glycaemic control protocol in the Malaysian intensive care unit. � 2016 The Authors. Final 2023-05-29T06:13:28Z 2023-05-29T06:13:28Z 2016 Article 10.22159/ijpps.2016v8s2.15218 2-s2.0-84994706822 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84994706822&doi=10.22159%2fijpps.2016v8s2.15218&partnerID=40&md5=edf8049ddace0c89b6a17f22b5f8f0d9 https://irepository.uniten.edu.my/handle/123456789/22929 8 40 42 All Open Access, Gold Innovare Academics Sciences Pvt. Ltd Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description glucose; insulin; adult; Article; blood glucose monitoring; critically ill patient; female; glycemic control; health care; hepatic clearance; human; insulin clearance; insulin sensitivity; intensive care unit; intensive glucose nutrition insulin model; major clinical study; Malaysia; male; renal clearance
author2 37059587300
author_facet 37059587300
Razak N.N.A.
Ahamad N.
Suhaimi F.
Jamaluddin U.
Ralib A.M.
format Article
author Razak N.N.A.
Ahamad N.
Suhaimi F.
Jamaluddin U.
Ralib A.M.
spellingShingle Razak N.N.A.
Ahamad N.
Suhaimi F.
Jamaluddin U.
Ralib A.M.
Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
author_sort Razak N.N.A.
title Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
title_short Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
title_full Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
title_fullStr Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
title_full_unstemmed Feasibility of an intensive control insulin-nutrition glucose model �ICING� with Malaysian critically-ill patient
title_sort feasibility of an intensive control insulin-nutrition glucose model �icing� with malaysian critically-ill patient
publisher Innovare Academics Sciences Pvt. Ltd
publishDate 2023
_version_ 1806423352034721792