Model-based glycemic control in a malaysian intensive care unit: Performance and safety study

Patient treatment; Stars; Blood glucose measurements; Control settings; Critically-ill patients; Glycemic control; Malaysians; Model based controls; Patient specific; Pilot trial; Intensive care units; glucose; Article; clinical assessment; cohort analysis; controlled study; disease severity; female...

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Main Authors: Abu-Samah A., Knopp J.L., Razak N.N.A., Razak A.A., Jamaludin U.K., Suhaimi F.M., Ralib A.M., Nor M.B.M., Chase J.G., Pretty C.G.
Other Authors: 56719596600
Format: Article
Published: Dove Medical Press Ltd 2023
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Institution: Universiti Tenaga Nasional
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spelling my.uniten.dspace-249932023-05-29T15:30:01Z Model-based glycemic control in a malaysian intensive care unit: Performance and safety study Abu-Samah A. Knopp J.L. Razak N.N.A. Razak A.A. Jamaludin U.K. Suhaimi F.M. Ralib A.M. Nor M.B.M. Chase J.G. Pretty C.G. 56719596600 57202741591 37059587300 56960052400 55330889600 36247893200 37031770900 57226799207 35570524900 6508290605 Patient treatment; Stars; Blood glucose measurements; Control settings; Critically-ill patients; Glycemic control; Malaysians; Model based controls; Patient specific; Pilot trial; Intensive care units; glucose; Article; clinical assessment; cohort analysis; controlled study; disease severity; female; glucose blood level; glycemic control; health care planning; human; hypoglycemia; incidence; intensive care unit; intervention study; major clinical study; Malaysian; male; patient safety; pilot study; protocol compliance; stochastic model Background: Stress-induced hyperglycemia is common in critically ill patients. A few forms of model-based glycemic control have been introduced to reduce this phenomena and among them is the automated STAR protocol which has been used in the Christchurch and Gyul� hospitals� intensive care units (ICUs) since 2010. Methods: This article presents the pilot trial assessment of STAR protocol which has been implemented in the International Islamic University Malaysia Medical Centre (IIUMMC) Hospital ICU since December 2017. One hundred and forty-two patients who received STAR treatment for more than 20 hours were used in the assessment. The initial results are presented to discuss the ability to adopt and adapt the model-based control framework in a Malaysian environment by analyzing its performance and safety. Results: Overall, 60.7% of blood glucose measurements were in the target band. Only 0.78% and 0.02% of cohort measurements were below 4.0 mmol/L and 2.2 mmol/L (the limitsfor mild and severe hypoglycemia, respectively). Treatment preference-wise, the clinical staff were favorable of longer intervention options when available. However, 1 hourly treatments were still used in 73.7% of cases. Conclusion: The protocol succeeded in achieving patient-specific glycemic control while maintaining safety and was trusted by nurses to reduce workload. Its lower performance results, however, give the indication for modification in some of the control settings to better fit the Malaysian environment. � 2019 Abu-Samah et al. Final 2023-05-29T07:30:01Z 2023-05-29T07:30:01Z 2019 Article 10.2147/MDER.S187840 2-s2.0-85068569706 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85068569706&doi=10.2147%2fMDER.S187840&partnerID=40&md5=7b7a8f0346b0224448e6721f56e85116 https://irepository.uniten.edu.my/handle/123456789/24993 12 215 226 All Open Access, Gold, Green Dove Medical Press Ltd Scopus
institution Universiti Tenaga Nasional
building UNITEN Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Tenaga Nasional
content_source UNITEN Institutional Repository
url_provider http://dspace.uniten.edu.my/
description Patient treatment; Stars; Blood glucose measurements; Control settings; Critically-ill patients; Glycemic control; Malaysians; Model based controls; Patient specific; Pilot trial; Intensive care units; glucose; Article; clinical assessment; cohort analysis; controlled study; disease severity; female; glucose blood level; glycemic control; health care planning; human; hypoglycemia; incidence; intensive care unit; intervention study; major clinical study; Malaysian; male; patient safety; pilot study; protocol compliance; stochastic model
author2 56719596600
author_facet 56719596600
Abu-Samah A.
Knopp J.L.
Razak N.N.A.
Razak A.A.
Jamaludin U.K.
Suhaimi F.M.
Ralib A.M.
Nor M.B.M.
Chase J.G.
Pretty C.G.
format Article
author Abu-Samah A.
Knopp J.L.
Razak N.N.A.
Razak A.A.
Jamaludin U.K.
Suhaimi F.M.
Ralib A.M.
Nor M.B.M.
Chase J.G.
Pretty C.G.
spellingShingle Abu-Samah A.
Knopp J.L.
Razak N.N.A.
Razak A.A.
Jamaludin U.K.
Suhaimi F.M.
Ralib A.M.
Nor M.B.M.
Chase J.G.
Pretty C.G.
Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
author_sort Abu-Samah A.
title Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
title_short Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
title_full Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
title_fullStr Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
title_full_unstemmed Model-based glycemic control in a malaysian intensive care unit: Performance and safety study
title_sort model-based glycemic control in a malaysian intensive care unit: performance and safety study
publisher Dove Medical Press Ltd
publishDate 2023
_version_ 1806424472028184576